Since I fairly new to the Regeneration deal I have a question about regenerating Hydra creatures with +1/+1 counters on them. My friend seems to think that if he Doom Blades, Supreme Verdicts, or any destroy creatures/target creature on my side of the field, that I can't use the regeneraton effect from Golgari Charm on my Primordial Hydra or Savageborn Hydra. He thinks that they become 0/0's and the counters thus go away so regenerating a Hydra with no +1/+1 counters on it since I cant recast it means my Hydras are dead. Is this correct?
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Those two spells Destroy. Regeneration replaces destruction, which means the destruction doesn't happen, which means it doesn't cause anything to go to the graveyard. If you cast the regeneration mode of Golgari Charm in response to Doom Blade or Supreme Verdict, your Hydras will be safe. They will not lose counters, enchantments, or equipment; they don't gain summoning sickness; spells targeting them don't lose sight of them; LTB and ETB abilities don't trigger; etc.
Regeneration will not save the Hydras from being sent to the graveyard as a result of having non-positive toughness, but nothing in the scenario you gave reduces their toughness (by removing +1/+1 counters or otherwise).
I think the confusion stems from a belief that regeneration causes the creature to leave the battlefield, but come back(like persist does).
But the rules just says to remove the damage and remove the creature from combat Instead of destroying it(it's a replacement effect). It is continuously on the battlefield during the entire process.