This question could be asked for just about any strategy, but to make it "not broad," I'll specify my strategy.
Suppose I was planning to follow a development strategy. After placing my initial two settlements, I'll establish two more, and upgrade all four to cities, bringing me up to eight VPs. After that, I'll buy development cards and hope to get two more VPs directly, or possibly through the largest army. I've picked this strategy because it minimizes my need for brick and wood. With two new settlements, two new roads, and four upgrades to cities, my initial resource requirements look something like this:
4 wood, 4 brick, 2 wool, 10 grain, 12 ore.
If I concentrate on sites that will get grain and ore what is a good way of making sure I obtain "enough" of the others?
- If I go for hexes that will get grain and ore with good numbers on the die such as six and eight, or at least five and nine, can I afford hexes where I get the others with fours and tens, or even threes and elevens, since I need proportionately less of them?
- If I have one settlement/city at a harbor, am I likely to generate enough of my "good" resources so I will be able to trade for the ones I need?
- Some development cards will give me two free roads. How helpful are these likely to be?
- I'm assuming that if I take an early lead, others will be unwilling to trade with me. Am I being too pessimistic?