2 fixed typo
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Others have answered how each expansion changes the game and what different behavior/strategies exist, so I'll comment on suggested order to buy expansions.

Subjective/situational aspects

I think it depends a lot on personal preference, whether you know anyone else with the game or intentintend to buy the game and how much money you want to spend.

Personal preference

I don't like Intrigue as much because I prefer peaceful games over attacking/defending, but there are some cards in Intrigue that I definitely would not want to miss out on! My wife likes Prosperity the most because she likes games to last longer (more base victory points available with colony added) and she tends to prefer big money strategies. Neither of us like Alchemy very much. If you are going to buy them all anyways then order of purchase may not matter in the end, but if you only want certain experiences then I suggest you read all the answers/tips/suggestions and familiarize yourself with the cards so you can carefully make your decision.

Friends

If you have a friend who enjoys playing base Dominion with you perhaps they might buy Intrigue so they will have a set of treasure/victory/curse cards themselves and then you could each decide who will buy the other expansions later. You can save money by ensuring you and your friends don't double up on games and expansions. If you are going over to someone else's home to play with them you won't need to carry as many boxes around and vice versa.

Cost

Can you afford to buy them all? Do you want to buy them all? Your choice of expansions may be very situational...

When everything is said and done...

There are great cards in each set and the game has evolved over time so if you're going to buy them all why not buy them in the order they were released? That's what we did and I don't have any complaints, in fact I've enjoyed every minute of our experience with Dominion! :)

Others have answered how each expansion changes the game and what different behavior/strategies exist, so I'll comment on suggested order to buy expansions.

Subjective/situational aspects

I think it depends a lot on personal preference, whether you know anyone else with the game or intent to buy the game and how much money you want to spend.

Personal preference

I don't like Intrigue as much because I prefer peaceful games over attacking/defending, but there are some cards in Intrigue that I definitely would not want to miss out on! My wife likes Prosperity the most because she likes games to last longer (more base victory points available with colony added) and she tends to prefer big money strategies. Neither of us like Alchemy very much. If you are going to buy them all anyways then order of purchase may not matter in the end, but if you only want certain experiences then I suggest you read all the answers/tips/suggestions and familiarize yourself with the cards so you can carefully make your decision.

Friends

If you have a friend who enjoys playing base Dominion with you perhaps they might buy Intrigue so they will have a set of treasure/victory/curse cards themselves and then you could each decide who will buy the other expansions later. You can save money by ensuring you and your friends don't double up on games and expansions. If you are going over to someone else's home to play with them you won't need to carry as many boxes around and vice versa.

Cost

Can you afford to buy them all? Do you want to buy them all? Your choice of expansions may be very situational...

When everything is said and done...

There are great cards in each set and the game has evolved over time so if you're going to buy them all why not buy them in the order they were released? That's what we did and I don't have any complaints, in fact I've enjoyed every minute of our experience with Dominion! :)

Others have answered how each expansion changes the game and what different behavior/strategies exist, so I'll comment on suggested order to buy expansions.

Subjective/situational aspects

I think it depends a lot on personal preference, whether you know anyone else with the game or intend to buy the game and how much money you want to spend.

Personal preference

I don't like Intrigue as much because I prefer peaceful games over attacking/defending, but there are some cards in Intrigue that I definitely would not want to miss out on! My wife likes Prosperity the most because she likes games to last longer (more base victory points available with colony added) and she tends to prefer big money strategies. Neither of us like Alchemy very much. If you are going to buy them all anyways then order of purchase may not matter in the end, but if you only want certain experiences then I suggest you read all the answers/tips/suggestions and familiarize yourself with the cards so you can carefully make your decision.

Friends

If you have a friend who enjoys playing base Dominion with you perhaps they might buy Intrigue so they will have a set of treasure/victory/curse cards themselves and then you could each decide who will buy the other expansions later. You can save money by ensuring you and your friends don't double up on games and expansions. If you are going over to someone else's home to play with them you won't need to carry as many boxes around and vice versa.

Cost

Can you afford to buy them all? Do you want to buy them all? Your choice of expansions may be very situational...

When everything is said and done...

There are great cards in each set and the game has evolved over time so if you're going to buy them all why not buy them in the order they were released? That's what we did and I don't have any complaints, in fact I've enjoyed every minute of our experience with Dominion! :)

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source | link

Others have answered how each expansion changes the game and what different behavior/strategies exist, so I'll comment on suggested order to buy expansions.

Subjective/situational aspects

I think it depends a lot on personal preference, whether you know anyone else with the game or intent to buy the game and how much money you want to spend.

Personal preference

I don't like Intrigue as much because I prefer peaceful games over attacking/defending, but there are some cards in Intrigue that I definitely would not want to miss out on! My wife likes Prosperity the most because she likes games to last longer (more base victory points available with colony added) and she tends to prefer big money strategies. Neither of us like Alchemy very much. If you are going to buy them all anyways then order of purchase may not matter in the end, but if you only want certain experiences then I suggest you read all the answers/tips/suggestions and familiarize yourself with the cards so you can carefully make your decision.

Friends

If you have a friend who enjoys playing base Dominion with you perhaps they might buy Intrigue so they will have a set of treasure/victory/curse cards themselves and then you could each decide who will buy the other expansions later. You can save money by ensuring you and your friends don't double up on games and expansions. If you are going over to someone else's home to play with them you won't need to carry as many boxes around and vice versa.

Cost

Can you afford to buy them all? Do you want to buy them all? Your choice of expansions may be very situational...

When everything is said and done...

There are great cards in each set and the game has evolved over time so if you're going to buy them all why not buy them in the order they were released? That's what we did and I don't have any complaints, in fact I've enjoyed every minute of our experience with Dominion! :)