I am wondering how well Takenoko plays with 2 players. What is the main problems only playing with 2, if any?
As far as the rules go the only difference is that the end of the game is triggered by one person completing 9 objective cards as opposed to 7 and 8 with 3 or 4 players respectively.
Takenoko works great as a 2 player game, there isn't much difference between the player counts. In fact, the game might be slightly less random with less people, but luck still plays a large role either way.