I've got the Neutralize All Threats and one credit. I make a run, say on a remote server, and access Space Camp. Since it costs 3 credits to trash, I can't afford the cost to trash it. Then I make a run, say on another remote server and access the Melange Mining Corp. Does Neutralize All Threats force me to trash it?
No, it doesn't force you. Neutralize All Threats triggers "the first time each turn you access a card with trash cost..." and whatever you did with that card is irrelevant for next accesses same turn.