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What are ways you can have a disease eradicated?

Is it if you get rid of all the cubes or do you have to find a cure first?

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You must first discover the cure before you can eradicate a disease. Otherwise, some diseases could begin the game eradicated. From the rulebook, page 4:

Treat Disease

If the last cube of a cured disease is removed from the board, this disease is eradicated. Flip its cure marker from its “vial” side to its “0” side.

Discover a Cure

[...]If no cubes of this color are on the board, this disease is now eradicated. Flip its cure marker from its “vial” side to its “0” side.

And:

Removing the last cube of a disease that is not cured has no effect.

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    However, if a disease that has no cube on the board becomes cured, it immediately becomes eradicated. The order in which things are done is not important.
    – ikegami
    Jun 1, 2018 at 6:57
  • I believe the rules quote under Discover a Cure makes that clear.
    – GendoIkari
    Jun 1, 2018 at 13:30

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