TL;DR: The odds are 1 in 1,733,866
To compute:
First calculate how many ways you can select a "winning hand":
Winning configuration count for your choice of suit x:
Each digit in the configuration represents either
- the number of aces of a suit, without regard to a specific suit
or
- the number of TJQK in suit X, without regard to a specific rank:
CASE 1
You might do it exactly (with no extra aces or extra cards of suit x):
8 aces: 2222 and 8 suit-X-non-aces (SXNA): 2222 with four other cards (neither Aces nor of suit X -- I'll call these "Off" cards): 4 I'll write this as case 1:
1) 2222 2222 4
There are C(4,2) ways of choosing each Ace and each SXNA. With four choices of X. And there are C(48,4) ways of choosing the other four cards
C(4,2)^8 * 4 * C(48,4) = 1,307,278,725,120 ways of drawing such a hand.
There are C(80,20) different hands, so dividing shows us a 1 in 2,704,332 chance of getting that kind of hand.
Other cases
The tricky part comes in factoring in the other ways to get it: drawing some of the extra aces and/or the extra SXNAs
Let's say you only draw 3 "Off" cards: getting an extra ace or an extra SXNA. There are two configurations to do this (cases 2 and 3):
2) 2223 2222 3
3) 2222 2223 3
And these configurations have a count (you have to choose which suit the extra Ace is in, or which rank the extra SXNA is)
The 2223 part has a count of C(4,1) = 4. This 4 representz the ways to select the order (if the columns corresponded to distinct suits/ranks): 2223, 2232, 2322, or 3222
The 2222 part still has a count of just one, but we can write that as C(4,4), meaning we're choosing four of the suits to be 2 (or four of the ranks in the case of SXNA).
So to make the counts explicit:
1) C(4,4)*C(4,4) -- choosing Aces 2s then SXNAs 2s
2) C(4,3)*C(1,1) * C(4,4) -- choosing Aces 2s then Aces 3s then SXNAs 2s
3) C(4,4) * C(4,3)*C(3,3) -- choosing Aces 2s then SXNAs 2s then SXNAs 3s
Continuing with having 2 "off" cards (and two extra Aces and/or SXNAs:
4) 2222 2224 2
5) 2222 2233 2
6) 2223 2223 2
7) 2224 2222 2
8) 2233 2222 2
And so on, making the whole table of configurations:
1) 2222 2222 4
2) 2222 2223 3
3) 2223 2222 3
4) 2222 2224 2
5) 2222 2233 2
6) 2223 2223 2
7) 2224 2222 2
8) 2233 2222 2
9) 2222 2234 1
10) 2222 2333 1
11) 2223 2224 1
12) 2223 2233 1
13) 2224 2223 1
14) 2233 2223 1
15) 2234 2222 1
16) 2333 2222 1
17) 2222 2244 0
18) 2222 2334 0
19) 2222 3333 0
20) 2223 2234 0
21) 2223 2333 0
22) 2224 2224 0
23) 2224 2233 0
24) 2233 2224 0
25) 2233 2233 0
26) 2234 2223 0
27) 2333 2223 0
28) 2244 2222 0
29) 2334 2222 0
30) 3333 2222 0
The count of each configuration is:
1) 2222 2222 4 C(4,4) * C(4,4)
2) 2222 2223 3 C(4,4) * C(4,3)*C(1,1)
3) 2223 2222 3 C(4,3)*C(1,1) * C(4,4)
4) 2222 2224 2 C(4,4) * C(4,3)*C(1,1)
5) 2222 2233 2 C(4,4) * C(4,2)*C(2,2)
6) 2223 2223 2 C(4,3)*C(1,1) * C(4,3)*C(1,1)
7) 2224 2222 2 C(4,3)*C(1,1) * C(4,4)
8) 2233 2222 2 C(4,2)*C(2,2) * C(4,4)
9) 2222 2234 1 C(4,4) * C(4,2)*C(2,1)*C(1,1)
10) 2222 2333 1 C(4,4) * C(4,1)*C(3,3)
11) 2223 2224 1 C(4,3)*C(1,1) * C(4,3)*C(1,1)
12) 2223 2233 1 C(4,3)*C(1,1) * C(4,2)*C(2,2)
13) 2224 2223 1 C(4,3)*C(1,1) * C(4,3)*C(1,1)
14) 2233 2223 1 C(4,2)*C(2,2) * C(4,3)*C(1,1)
15) 2234 2222 1 C(4,2)*C(2,1)*C(1,1) * C(4,4)
16) 2333 2222 1 C(4,1)*C(3,3) * C(4,4)
17) 2222 2244 0 C(4,4) * C(4,2)*C(2,2)
18) 2222 2334 0 C(4,4) * C(4,1)*C(3,2)*C(1,1)
19) 2222 3333 0 C(4,4) * C(4,4)
20) 2223 2234 0 C(4,3)*C(1,1) * C(4,2)*C(2,1)*C(1,1)
21) 2223 2333 0 C(4,3)*C(1,1) * C(4,1)*C(3,3)
22) 2224 2224 0 C(4,3)*C(1,1) * C(4,3)*C(1,1)
23) 2224 2233 0 C(4,3)*C(1,1) * C(4,2)*C(2,2)
24) 2233 2224 0 C(4,2)*C(2,2) * C(4,3)*C(1,1)
25) 2233 2233 0 C(4,2)*C(2,2) * C(4,2)*C(2,2)
26) 2234 2223 0 C(4,2)*C(2,1)*C(1,1) * C(4,3)*C(1,1)
27) 2333 2223 0 C(4,1)*C(3,3) * C(4,3)*C(1,1)
28) 2244 2222 0 C(4,2)*C(2,2) * C(4,4)
29) 2334 2222 0 C(4,1)*C(3,2)*C(1,1) * C(4,4)
30) 3333 2222 0 C(4,4) * C(4,4)
And finally we have to factor in the group count: how many ways can we select the N aces or a given suit from the 4 available? For 2222, the count is C(4,2)^4 : choose 2 of the 4 available aces for each suit. for the Aces and the SXNAs, there are four cards available for each column (four suits or four ranks). For the Off column, there are 48 available cards (four copies of four non-ace ranks in three suits).
1) 2222 2222 4 C(4,2)^8*C(48,4)
2) 2222 2223 3 C(4,2)^7*C(4,3)*C(48,3)
3) 2223 2222 3 C(4,2)^7*C(4,3)*C(48,3)
4) 2222 2224 2 C(4,2)^7*C(4,4)*C(48,2)
5) 2222 2233 2 C(4,2)^6*C(4,3)^2*C(48,2)
6) 2223 2223 2 C(4,2)^6*C(4,3)^2*C(48,2)
7) 2224 2222 2 C(4,2)^7*C(4,4)*C(48,2)
8) 2233 2222 2 C(4,2)^6*C(4,3)^2*C(48,2)
9) 2222 2234 1 C(4,2)^6*C(4,3)*C(4,4)*C(48,1)
10) 2222 2333 1 C(4,2)^5*C(4,3)^3*C(48,1)
11) 2223 2224 1 C(4,2)^6*C(4,3)*C(4,4)*C(48,1)
12) 2223 2233 1 C(4,2)^5*C(4,3)^3*C(48,1)
13) 2224 2223 1 C(4,2)^6*C(4,3)*C(4,4)*C(48,1)
14) 2233 2223 1 C(4,2)^5*C(4,3)^3*C(48,1)
15) 2234 2222 1 C(4,2)^6*C(4,3)*C(4,4)*C(48,1)
16) 2333 2222 1 C(4,2)^5*C(4,3)^3*C(48,1)
17) 2222 2244 0 C(4,2)^6*C(4,4)^2
18) 2222 2334 0 C(4,2)^5*C(4,3)^2*C(4,4)
19) 2222 3333 0 C(4,2)^4*C(4,3)^4
20) 2223 2234 0 C(4,2)^5*C(4,3)^2*C(4,4)
21) 2223 2333 0 C(4,2)^4*C(4,3)^4
22) 2224 2224 0 C(4,2)^6*C(4,4)^2
23) 2224 2233 0 C(4,2)^5*C(4,3)^2*C(4,4)
24) 2233 2224 0 C(4,2)^5*C(4,3)^2*C(4,4)
25) 2233 2233 0 C(4,2)^4*C(4,3)^4
26) 2234 2223 0 C(4,2)^5*C(4,3)^2*C(4,4)
27) 2333 2223 0 C(4,2)^4*C(4,3)^4
28) 2244 2222 0 C(4,2)^6*C(4,4)^2
29) 2334 2222 0 C(4,2)^5*C(4,3)^2*C(4,4)
30) 3333 2222 0 C(4,2)^4*C(4,3)^4
To find the number of each case, just multiply 4 (the number of choices of suit X) by the configuration count and the group count:
1) 2222 2222 4 -- 1,307,278,725,120
2) 2222 2223 3 -- 309,873,475,584
3) 2223 2222 3 -- 309,873,475,584
4) 2222 2224 2 -- 5,052,284,928
5) 2222 2233 2 -- 20,209,139,712
6) 2223 2223 2 -- 53,891,039,232
7) 2224 2222 2 -- 5,052,284,928
8) 2233 2222 2 -- 20,209,139,712
9) 2222 2234 1 -- 429,981,696
10) 2222 2333 1 -- 382,205,952
11) 2223 2224 1 -- 573,308,928
12) 2223 2233 1 -- 2,293,235,712
13) 2224 2223 1 -- 573,308,928
14) 2233 2223 1 -- 2,293,235,712
15) 2234 2222 1 -- 429,981,696
16) 2333 2222 1 -- 382,205,952
17) 2222 2244 0 -- 1,119,744
18) 2222 2334 0 -- 5,971,968
19) 2222 3333 0 -- 1,327,104
20) 2223 2234 0 -- 23,887,872
21) 2223 2333 0 -- 21,233,664
22) 2224 2224 0 -- 2,985,984
23) 2224 2233 0 -- 11,943,936
24) 2233 2224 0 -- 11,943,936
25) 2233 2233 0 -- 47,775,744
26) 2234 2223 0 -- 23,887,872
27) 2333 2223 0 -- 21,233,664
28) 2244 2222 0 -- 1,119,744
29) 2334 2222 0 -- 5,971,968
30) 3333 2222 0 -- 1,327,104
For a total of 2,038,978,759,680
Dividing by the number of hands, C(80,20) = 3,535,316,142,212,180,000
We find the odds to be about 1 in 1,733,866
(nb: there's no reason you have to handle the aces distinctly from the SXNAs: there are four of each. So you could reduce the number of cases. They're left distinct here for approachability and transparency.)