For example, there is a free "r" on the board. I have the letters "endueoe". I could do either the word "endure" or "enduro". The former would leave me with an 'o' and 'e'. The latter would leave me with an 'e' and 'e'. I wonder if an "oe" combination would be better or worse than an "ee" vowel combination. I will draw 5 letters next turn, and I want to see if what advantage I would have for each. I know it depends on much is left in the tile bag, but in general, what are the best vowel combinations, like possibly in ranking?