This is more a question for the big games with a lot of investigators. A few non-critical tokens seem to be able to run out, and I can't find anything about those specific tokens in the rules.
Do you just rip a piece of paper and create a clue token or are they out when out? I do know some of the tokens (like portals) awaken the Ancient One when they run out, but for the others there are no mentions in the rules (or I'm just missing them) about what to do when there are none left in the box.
In an 8 player game I've had this problem with Clue, Stamina, Sanity, Money and Explored (those you get once coming back from a portal) tokens. I don't believe the intention is to get sucked back into the portal just because there are no tokens left, but I might be wrong.
Any ideas about official rulings in these cases?